4-bromo-2-iodobenzyl alcohol
$250.00
CAS No.: 1261438-69-0
Catalog No.: 194041
Purity: 95%
MF: C7H6BrIO
MW: 312.932
Storage: 2-8 degree Celsius
SMILES: BrC1=CC(=C(CO)C=C1)I
Catalog No.: 194041
Purity: 95%
MF: C7H6BrIO
MW: 312.932
Storage: 2-8 degree Celsius
SMILES: BrC1=CC(=C(CO)C=C1)I
4-bromo-2-iodobenzyl alcohol; CAS No.: 1261438-69-0; 4-bromo-2-iodobenzyl alcohol. PROPERTIES: 4-bromo-2-iodobenzyl alcohol is a crystalline solid with a molecular weight of 322.0 g/mol. It typically exhibits a melting point in the range of 85-88 C and limited water solubility, though it dissolves readily in organic solvents such as methanol, ethanol, and dichloromethane. The compound contains reactive functional groups including a hydroxyl group, bromine substituent, and iodine substituent, which contribute to its chemical versatility. For optimal storage, it should be kept in a tightly sealed container at temperatures below 20 C, preferably under inert atmosphere to prevent potential oxidation of the alcohol group. Safety considerations include wearing appropriate protective clothing, gloves, and eye/face protection to minimize exposure risk. The compound may cause eye irritation and skin irritation, and in case of accidental ingestion, immediate medical attention is advised. APPLICATIONS: 4-bromo-2-iodobenzyl alcohol serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted kinase inhibitors for cancer therapy. Its unique substitution pattern allows for selective derivatization, making it suitable for constructing bioactive scaffolds, as reported in oncology research publications. In materials science, the compound functions as a building block for certain types of conductive polymers, where the electron-withdrawing bromine and iodine substituents create a balanced electronic environment. Additionally, it is utilized in the preparation of specialty dyes and pigments, particularly those requiring thermal stability. Through chemical modification of the hydroxyl group, it can be converted into various esters, ethers, or amines, expanding its application scope in organic synthesis, as described in recent advances in heterocyclic chemistry. The presence of both bromine and iodine substituents provides convenient handles for further functionalization, such as in cross-coupling reactions.
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