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4-amino-6-methylpyrimidine-5-carbonitrile; CAS No.: 76574-44-2; As a worldwide chemical supplier, ChemShuttle supplies 4-amino-6-methylpyrimidine-5-carbonitrile for kinase hinge region mimetics. The cyano group participates in dipole interactions with backbone carbonyls, while the methyl group enhances hydrophobic packing. Our kinase panel screening identifies selective inhibitors from fragment libraries.