4,5,6,7-Tetrahydro-1H-indazol-5-amine dihydrochloride
$360.00
CAS No.: 74197-17-4
Catalog No.: 192660
Purity: 95%
MF: C7H13Cl2N3
MW: 210.108
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.N1N=CC=2CC(CCC12)N
Catalog No.: 192660
Purity: 95%
MF: C7H13Cl2N3
MW: 210.108
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.N1N=CC=2CC(CCC12)N
4,5,6,7-Tetrahydro-1H-indazol-5-amine dihydrochloride; CAS No.: 74197-17-4; 4,5,6,7-Tetrahydro-1H-indazol-5-amine dihydrochloride. PROPERTIES: This tetrahydroindazole amine salt has molecular formula C8H13Cl2N3. It typically appears as a white crystalline powder. The 4,5,6,7-tetrahydro-1H-indazol-5-amine dihydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in methanol and ethanol. Its melting point is approximately 230-235 C (with decomposition), and it has a molecular weight of about 218.1 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The dihydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 4,5,6,7-tetrahydro-1H-indazol-5-amine dihydrochloride serves as a critical intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the tetrahydroindazole ring provides essential binding interactions with receptor subtypes (as reported in medicinal chemistry literature). The amine group provides hydrogen bonding capabilities important for receptor binding. Additionally, the compound functions as a building block in the preparation of agrochemicals with fungicidal activity, though this application is mentioned only for informational purposes per your request. The amine group can be further functionalized through alkylation or acylation reactions to produce various derivatives for chemical research applications.
Reviews
Write Your Own Review