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3-hydroxy-1-(4-methoxyphenyl)cyclobutanecarboxylic acid; CAS No.: 1353636-86-8; 3-hydroxy-1-(4-methoxyphenyl)cyclobutanecarboxylic acid. PROPERTIES: This compound is a 3-hydroxy-1-(4-methoxyphenyl)cyclobutanecarboxylic acid appearing as white crystalline powder. Its molecular weight is approximately 254.26 g/mol. It has melting point around 130-135 C. The compound is moderately soluble in common organic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 25 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 3-hydroxy-1-(4-methoxyphenyl)cyclobutanecarboxylic acid is utilized in organic synthesis as hydroxyphenylcyclobutane building block as detailed in Tetrahedron journal. It's employed in preparation of certain kinase inhibitors mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing phenylcyclobutane-containing pharmaceuticals reported in Bioorganic & Medicinal Chemistry Letters. The hydroxyl and methoxy groups provide valuable sites for further functionalization in drug discovery projects.