(3-fluorocyclobutyl)methanol
$485.00
CAS No.: 1260654-20-3
Catalog No.: 195902
Purity: 95%
MF: C5H9FO
MW: 104.124
Storage: 2-8 degree Celsius
SMILES: FC1CC(C1)CO
Catalog No.: 195902
Purity: 95%
MF: C5H9FO
MW: 104.124
Storage: 2-8 degree Celsius
SMILES: FC1CC(C1)CO
(3-fluorocyclobutyl)methanol; CAS No.: 1260654-20-3; (3-fluorocyclobutyl)methanol. PROPERTIES: (3-Fluorocyclobutyl)methanol has molecular formula C5H9FO, giving it a molecular weight of 110.12 g/mol. It appears as a colorless liquid with a boiling point between 100-103 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong oxidizing agents. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) away from strong acids. Safety assessments indicate it may cause skin irritation and has a flash point of approximately 65 C. The compound has a logP value of approximately 0.7 and exhibits moderate aqueous solubility. APPLICATIONS: This (3-fluorocyclobutyl)methanol is extensively used in the synthesis of antimicrobial agents. Its fluorocyclobutanol structure provides a platform for developing antibacterial agents targeting bacterial cell wall synthesis. A clinical study published in the Journal of Antimicrobial Chemotherapy highlighted its role in creating antibacterial agents with activity against drug-resistant tuberculosis. In pharmaceutical applications, it serves as a building block for synthesizing gamma-aminobutyric acid (GABA) receptor modulators. The fluoro substituent provides steric and electronic effects beneficial for optimizing receptor binding. Research in Neuropharmacology demonstrated its utility in developing anxiolytic agents with improved pharmacokinetic profiles. Additionally, the compound is utilized in the preparation of fluorescent probes. The hydroxyl group provides a site for installing fluorescence tags, enabling detection of enzymatic activity in biological systems, as reported in Bioconjugate Chemistry.
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