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3-bromoquinoline-7-carboxamide; CAS No.: 1956371-42-8; 3-bromoquinoline-7-carboxamide. PROPERTIES: 3-bromoquinoline-7-carboxamide is a crystalline solid with a molecular weight of 255.1 g/mol. It has a melting point between 195 and 198 C and is moderately soluble in dimethylformamide and dimethyl sulfoxide. The compound is sensitive to light and should be stored in amber glass containers. It is stable under normal laboratory conditions but may decompose upon exposure to strong acids or bases. When handling, protective eyewear and gloves should be worn, and in case of eye contact, immediate rinsing with water is advised. APPLICATIONS: 3-bromoquinoline-7-carboxamide serves as a valuable intermediate in the synthesis of pharmaceuticals, particularly in the development of anticancer and antiviral agents. The bromine substituent allows for diverse substitution reactions, while the carboxamide group provides hydrogen bonding capabilities useful in drug-receptor interactions. In medicinal chemistry, 3-bromoquinoline-7-carboxamide is employed in the design of compounds targeting specific protein-protein interactions. It also functions as a building block in the synthesis of fluorescent dyes, where its quinoline core contributes to emission characteristics. Additionally, the compound is used in the preparation of metal complexes for catalytic applications in organic transformations. These applications are commonly found in pharmaceutical research institutions and chemical manufacturing facilities specializing in heterocyclic chemistry.