3-bromoisoquinolin-4-amine
$250.00
CAS No.: 40073-37-8
Catalog No.: 196245
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC=1N=CC2=CC=CC=C2C1N
Catalog No.: 196245
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC=1N=CC2=CC=CC=C2C1N
3-bromoisoquinolin-4-amine; CAS No.: 40073-37-8; 3-bromoisoquinolin-4-amine. PROPERTIES: This compound features a 3-bromoisoquinolin-4-amine structure, combining a bromine atom and an amine group on the isoquinoline framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 219.0 g/mol (C8H6BrN2). The melting point ranges between 130-135 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 3-Bromoisoquinolin-4-amine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 3-bromoisoquinolin-4-amine structure allows for participation in various reactions, including palladium-catalyzed cross-coupling reactions at the bromine position and nucleophilic substitution at the amine group. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The bromine atom provides a handle for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel bromoisoquinoline derivatives based on the 3-bromoisoquinolin-4-amine scaffold.
Reviews
Write Your Own Review