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3-bromo-7-ethoxyquinoline; CAS No.: 1476078-53-1; 3-bromo-7-ethoxyquinoline. PROPERTIES: 3-bromo-7-ethoxyquinoline is a crystalline substance with a molecular weight of 266.1 g/mol. It has a melting point between 68 and 72 C and moderate solubility in organic solvents such as ethanol and acetone. The compound is light-sensitive and should be stored in amber glass containers away from direct sunlight. It is stable under normal laboratory conditions but decomposes upon exposure to strong acids or bases. When handling, standard laboratory precautions should be observed, including avoiding skin contact and using proper ventilation. APPLICATIONS: 3-bromo-7-ethoxyquinoline is utilized as a synthetic intermediate in the production of pharmaceuticals, particularly in the development of antimalarial and antibacterial agents. Its bromine substituent provides a site for further functionalization, making it valuable in medicinal chemistry. The ethoxy group enhances solubility properties, which is beneficial in drug formulation research. In organic synthesis, 3-bromo-7-ethoxyquinoline serves as a building block for more complex heterocyclic systems. It is also employed in the synthesis of fluorescent dyes, where its quinoline core contributes to emission characteristics. These applications are commonly found in pharmaceutical research institutions and specialized chemical manufacturing facilities, where the compound's unique substituent pattern facilitates diverse chemical transformations.