3-(benzyloxy)-2,2-dimethylcyclobutan-1-one
$365.00
CAS No.: 2063-92-5
Catalog No.: 195556
Purity: 95%
MF: C13H16O2
MW: 204.269
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1C(C(C1)=O)(C)C
Catalog No.: 195556
Purity: 95%
MF: C13H16O2
MW: 204.269
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1C(C(C1)=O)(C)C
3-(benzyloxy)-2,2-dimethylcyclobutan-1-one; CAS No.: 2063-92-5; 3-(benzyloxy)-2,2-dimethylcyclobutan-1-one. PROPERTIES: 3-(benzyloxy)-2,2-dimethylcyclobutan-1-one is a colorless to pale yellow oil with molecular formula C12H16O2. It exhibits a boiling point around 145-150 C at 10 mmHg and moderate thermal stability. The compound shows good solubility in ethyl acetate and moderate solubility in hexane. Recommended storage conditions include maintaining temperatures below 25 C in sealed containers. Safety considerations involve using closed-system transfer equipment when handling large quantities to prevent exposure and avoiding release into the environment to prevent ecological harm. APPLICATIONS: This benzyloxy-protected cyclobutanone serves as a key intermediate in the synthesis of prostaglandin analogs, where the 3-(benzyloxy)-2,2-dimethylcyclobutan-1-one group provides structural similarity to the cyclopentane core of prostaglandins (Journal of Medicinal Chemistry). In organic synthesis, the compound is used as a building block for constructing medium-sized carbocycles through ring-opening reactions (Synthesis). Furthermore, its ketone functionality enables oximation reactions for the development of bioactive hydroxylamine derivatives used in anti-tuberculosis research (Antimicrobial Agents and Chemotherapy).
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