3,3-difluoro-5-hydroxypiperidin-2-one
$395.00
CAS No.: 1256080-98-4
Catalog No.: 171966
Purity: 95%
MF: C5H7F2NO2
MW: 151.112
Storage: 2-8 degree Celsius
SMILES: OC1CNC(=O)C(F)(F)C1
Catalog No.: 171966
Purity: 95%
MF: C5H7F2NO2
MW: 151.112
Storage: 2-8 degree Celsius
SMILES: OC1CNC(=O)C(F)(F)C1
3,3-difluoro-5-hydroxypiperidin-2-one; CAS No.: 1256080-98-4; As part of their Library of Compounds, ChemShuttle offers 3,3-difluoro-5-hydroxypiperidin-2-one. This fluorinated lactam serves as a screening compound for GABA analog development and proteolysis-targeting chimera (PROTAC) design. The hydroxyl group enables PEGylation for improving pharmacokinetics, while the difluoro substitution enhances blood-brain barrier penetration. ChemShuttle provides crystallographic data confirming the boat conformation stabilized by fluorine atoms. Applications include cognitive disorder therapeutics and lysine-specific demethylase inhibitor development. Custom services include preparation of deuterated analogs at the hydroxyl position for metabolic studies.
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