2-(trifluoromethyl)quinolin-6-ol
$500.00
CAS No.: 143465-21-8
Catalog No.: 192220
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C1=NC2=CC=C(C=C2C=C1)O)(F)F
Catalog No.: 192220
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C1=NC2=CC=C(C=C2C=C1)O)(F)F
2-(trifluoromethyl)quinolin-6-ol; CAS No.: 143465-21-8; 2-(trifluoromethyl)quinolin-6-ol. PROPERTIES: 2-(trifluoromethyl)quinolin-6-ol is a crystalline powder with molecular formula C9H5F3NO. It has a melting point of approximately 110-115 C and exhibits limited aqueous solubility but good solubility in DMSO. Proper storage involves maintaining in a sealed container at room temperature away from heat sources. Safety considerations include wearing protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This trifluoromethyl-substituted quinoline alcohol is employed in the development of antimicrobial agents. The hydroxyl group at position 6 allows for glycosylation, creating fluoroquinolone antibiotics with enhanced antibacterial spectra as reported in pharmaceutical chemistry journals. In bioanalytical applications, 2-(trifluoromethyl)quinolin-6-ol serves as a fluorescent probe for detecting specific metal ions. According to analytical chemistry research, the quinoline scaffold's fluorescence is quenched upon metal coordination, enabling sensitive detection methods with limits approaching nanomolar concentrations.
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