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2'-(trifluoromethyl)biphenyl-4-carboxylic acid; CAS No.: 198205-79-7; 2'-(trifluoromethyl)biphenyl-4-carboxylic acid. PROPERTIES: This trifluoromethyl-substituted biphenyl carboxylic acid features molecular formula C??H??F?O? with molecular weight 261.22 g/mol. Appears as a crystalline solid. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 140-145 C. Exhibits IR absorption for carboxylic acid group. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a trifluoromethyl-substituted carboxylic acid, 2'-(trifluoromethyl)biphenyl-4-carboxylic acid is used in pharmaceutical synthesis. It serves as key intermediate in constructing biaryl-containing pharmaceuticals, where the carboxylic acid group forms amide bonds. Also used in materials science as monomer for preparing polyaryl acid polymers with enhanced thermal stability. In pesticide chemistry, it functions as building block in the synthesis of herbicides, where the trifluoromethyl group provides bioactivity.