2-nitro-4-(trifluoromethyl)benzyl alcohol
$250.00
CAS No.: 133605-27-3
Catalog No.: 193942
Purity: 95%
MF: C8H6F3NO3
MW: 221.134
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C1=C(CO)C=CC(=C1)C(F)(F)F
Catalog No.: 193942
Purity: 95%
MF: C8H6F3NO3
MW: 221.134
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C1=C(CO)C=CC(=C1)C(F)(F)F
2-nitro-4-(trifluoromethyl)benzyl alcohol; CAS No.: 133605-27-3;2-nitro-4-(trifluoromethyl)benzyl alcohol. PROPERTIES: 2-nitro-4-(trifluoromethyl)benzyl alcohol is a nitrated and trifluoromethylated aromatic alcohol with molecular formula C8H7F3NO3. It typically exists as a colorless liquid with a boiling point around 135-140 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic nitrogen oxides and fluorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The nitro and trifluoromethyl substituents provide strong electron-withdrawing effects that influence reactivity and selectivity, while the hydroxyl group offers sites for further functionalization (The Journal of Organic Chemistry). In pharmaceutical development, 2-nitro-4-(trifluoromethyl)benzyl alcohol contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
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