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2-methylpropan-2-yl (3R,4R)-4-hydroxy-3-(hydroxymethyl)tetrahydropyrrole-1-carboxylate; CAS No.: 635319-09-4; 2-methylpropan-2-yl (3R,4R)-4-hydroxy-3-(hydroxymethyl)tetrahydropyrrole-1-carboxylate. PROPERTIES: This compound is a 2-methylpropan-2-yl (3R,4R)-4-hydroxy-3-(hydroxymethyl)tetrahydropyrrole-1-carboxylate appearing as white amorphous solid. Its molecular weight is approximately 265.30 g/mol. It has characteristic mild odor. The compound is moderately soluble in common organic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 20 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 2-methylpropan-2-yl (3R,4R)-4-hydroxy-3-(hydroxymethyl)tetrahydropyrrole-1-carboxylate is utilized in asymmetric synthesis as chiral tetrahydropyrrolidine building block as detailed in Journal of Organic Chemistry. It's employed in preparation of certain HIV integrase inhibitors mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing carbohydrate-containing pharmaceuticals reported in Carbohydrate Research. The hydroxyl groups provide valuable sites for further functionalization in drug discovery applications.