2-methyl-5-nitropyrimidin-4(3H)-one
$225.00
CAS No.: 99893-01-3
Catalog No.: 192973
Purity: 95%
MF: C5H5N3O3
MW: 155.113
Storage: 2-8 degree Celsius
SMILES: CC1=NC=C(C(N1)=O)[N+](=O)[O-]
Catalog No.: 192973
Purity: 95%
MF: C5H5N3O3
MW: 155.113
Storage: 2-8 degree Celsius
SMILES: CC1=NC=C(C(N1)=O)[N+](=O)[O-]
2-methyl-5-nitropyrimidin-4(3H)-one; CAS No.: 99893-01-3; 2-methyl-5-nitropyrimidin-4(3H)-one. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C5H4N3O3 and a molecular weight of 160.09 g/mol. It demonstrates a melting point in the range of 178-182 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 2-methyl-5-nitropyrimidin-4(3H)-one may release toxic fumes upon heating. The nitro group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 2-methyl-5-nitropyrimidin-4(3H)-one serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its nitro substituent enables reduction to generate amino groups for further functionalization. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrimidinone ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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