2-hydroxy-5-(trifluoromethyl)benzonitrile
$400.00
CAS No.: 142167-36-0
Catalog No.: 196676
Purity: 95%
MF: C8H4F3NO
MW: 187.12
Storage: 2-8 degree Celsius
SMILES: OC1=C(C#N)C=C(C=C1)C(F)(F)F
Catalog No.: 196676
Purity: 95%
MF: C8H4F3NO
MW: 187.12
Storage: 2-8 degree Celsius
SMILES: OC1=C(C#N)C=C(C=C1)C(F)(F)F
2-hydroxy-5-(trifluoromethyl)benzonitrile; CAS No.: 142167-36-0; 2-hydroxy-5-(trifluoromethyl)benzonitrile. PROPERTIES: This trifluoromethyl-substituted hydroxy nitrile features molecular formula C?H?F?NO with molecular weight 193.12 g/mol. Exists as a crystalline solid. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 100-105 C. Exhibits IR absorption for hydroxyl and nitrile groups. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a trifluoromethyl-substituted nitrile, 2-hydroxy-5-(trifluoromethyl)benzonitrile is used in beta-blocker synthesis. The nitrile group hydrolyzes to carboxylic acid, forming amide functionality. Also used in fluorescent probe synthesis, enabling conjugation via click chemistry. In materials science, it enhances thermal stability in polyacrylonitrile fibers due to trifluoromethyl substituents.
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