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2-fluorobenzene-1,4-diol; CAS No.: 55660-73-6; 2-fluorobenzene-1,4-diol. PROPERTIES: This fluoro-substituted benzene-1,4-diol features molecular formula C?H?FO? with molecular weight 137.10 g/mol. It typically exists as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for hydroxyl groups (~3300 cm??) and C-F stretches (~1300-1100 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a fluoro-substituted benzene-1,4-diol, 2-fluorobenzene-1,4-diol is predominantly utilized in the synthesis of fungicides. It serves as a key intermediate in constructing strobilurin-class fungicides, where the fluoro and diol groups provide valuable binding affinity for fungal enzymes as demonstrated in pesticide chemistry research (Pest Management Science). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its diol functionality enables conjugation to biomolecules via oxime formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the fluoro substituent contributes to improved flame retardancy and mechanical properties (Polymer International).