2-fluoro-5-methylanisole
$300.00
CAS No.: 63762-78-7
Catalog No.: 197133
Purity: 95%
MF: C8H9FO
MW: 140.157
Storage: 2-8 degree Celsius
SMILES: FC1=C(C=C(C=C1)C)OC
Catalog No.: 197133
Purity: 95%
MF: C8H9FO
MW: 140.157
Storage: 2-8 degree Celsius
SMILES: FC1=C(C=C(C=C1)C)OC
2-fluoro-5-methylanisole; CAS No.: 63762-78-7; 2-fluoro-5-methylanisole. PROPERTIES: This fluoro-methyl-substituted anisole features molecular formula C?H?FO with molecular weight 146.16 g/mol. It typically exists as a colorless liquid. Soluble in non-polar and slightly polar organic solvents like hexanes and ethyl acetate. Boiling point approximately 140-145 C. Exhibits IR absorption for C-F (~1300-1100 cm??) and aromatic C-H stretches. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a fluoro-methyl-substituted anisole, 2-fluoro-5-methylanisole is predominantly utilized in the synthesis of flavor and fragrance compounds. It serves as a key intermediate in constructing macrocyclic musk fragrances, where the fluoro and methoxy groups provide valuable olfactory properties as demonstrated in fragrance chemistry research (Perfumer & Flavorist). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its anisole framework enables conjugation to fluorophores with enhanced photostability (Journal of the American Chemical Society). In materials science, it functions as a monomer for preparing polyaryl ethers with enhanced thermal stability, where the fluoro substituent contributes to improved flame retardancy and mechanical properties (Polymer Chemistry).
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