2-bromo-4-(trifluoromethyl)benzyl amine
$200.00
CAS No.: 1001109-50-7
Catalog No.: 193897
Purity: 95%
MF: C8H7BrF3N
MW: 254.049
Storage: 2-8 degree Celsius
SMILES: BrC1=C(CN)C=CC(=C1)C(F)(F)F
Catalog No.: 193897
Purity: 95%
MF: C8H7BrF3N
MW: 254.049
Storage: 2-8 degree Celsius
SMILES: BrC1=C(CN)C=CC(=C1)C(F)(F)F
2-bromo-4-(trifluoromethyl)benzyl amine; CAS No.: 1001109-50-7;2-bromo-4-(trifluoromethyl)benzyl amine. PROPERTIES: 2-bromo-4-(trifluoromethyl)benzyl amine is a brominated and trifluoromethylated aromatic amine with molecular formula C9H8BrF3N. It typically exists as a colorless liquid with a boiling point around 140-145 C. The compound has limited water solubility but dissolves well in organic solvents like ethanol or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong oxidizing agents, releasing toxic nitrogen-containing fumes. Proper storage involves keeping it in tightly sealed containers below 30 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The bromo substituent provides a site for cross-coupling reactions to form biaryl structures, while the trifluoromethyl and amine groups offer additional functionality for further elaboration (The Journal of Organic Chemistry). In pharmaceutical development, 2-bromo-4-(trifluoromethyl)benzyl amine contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
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