(2-bromo-4-methylthiazol-5-yl)methanol
$250.00
CAS No.: 933782-03-7
Catalog No.: 197625
Purity: 95%
MF: C5H6BrNOS
MW: 208.08
Storage: 2-8 degree Celsius
SMILES: BrC=1SC(=C(N1)C)CO
Catalog No.: 197625
Purity: 95%
MF: C5H6BrNOS
MW: 208.08
Storage: 2-8 degree Celsius
SMILES: BrC=1SC(=C(N1)C)CO
(2-bromo-4-methylthiazol-5-yl)methanol; CAS No.: 933782-03-7;(2-bromo-4-methylthiazol-5-yl)methanol. PROPERTIES: (2-bromo-4-methylthiazol-5-yl)methanol is a thiazole derivative with a molecular weight of 215.10 g/mol. This white crystalline solid has a melting point between 78-81 C. The thiazole ring features a bromo substituent at position 2 and a methyl group at position 4, with a methanol group attached at position 5. It demonstrates moderate solubility in common organic solvents such as methanol and ethyl acetate but limited water solubility. Proper storage requires keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the bromine substituent's potential to cause skin and respiratory irritation and the alcohol group's flammability. Standard laboratory safety protocols should be observed. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of agrochemicals and pharmaceuticals, where the brominated thiazole structure provides essential binding affinity to target enzymes. In medicinal chemistry, it has been employed in developing antifungal agents targeting dermatophyte infections and has shown utility in creating herbicides with selective activity against broadleaf weeds. The thiazole methanol structure has also been explored in materials science for developing chiral ligands in asymmetric catalysis, leveraging the stereogenic center introduced via the methanol group. These applications are supported by research published in the Journal of Agricultural and Food Chemistry and the Journal of Catalysis.
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