(2-bromo-4-methylthiazol-5-yl)methanamine hydrobromide
$995.00
CAS No.: 1823931-45-8
Catalog No.: 197618
Purity: 95%
MF: C5H8Br2N2S
MW: 288.008
Storage: 2-8 degree Celsius
SMILES: Br.BrC=1SC(=C(N1)C)CN
Catalog No.: 197618
Purity: 95%
MF: C5H8Br2N2S
MW: 288.008
Storage: 2-8 degree Celsius
SMILES: Br.BrC=1SC(=C(N1)C)CN
(2-bromo-4-methylthiazol-5-yl)methanamine hydrobromide; CAS No.: 1823931-45-8;(2-bromo-4-methylthiazol-5-yl)methanamine hydrobromide. PROPERTIES: (2-bromo-4-methylthiazol-5-yl)methanamine hydrobromide is a thiazole derivative with a molecular weight of 264.09 g/mol (base). This white crystalline solid has a melting point between 210-213 C. The thiazole ring features a bromo substituent at position 2 and a methyl group at position 4, with a methanamine group attached at position 5, forming a hydrobromide salt. It exhibits limited solubility in water but dissolves in polar organic solvents like methanol and DMSO. The compound is hygroscopic and should be stored in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the bromine substituent's toxicity and the amine group's basicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of antimicrobial and antiparasitic agents, where the brominated thiazole structure provides essential binding affinity to target enzymes. In pharmaceutical development, it has been employed in creating antifungal medications targeting Candida species and has shown utility in developing antiprotozoal agents for treating parasitic infections. The thiazole methanamine structure has also been explored in agrochemical formulations as a component of selective herbicides, leveraging the bromine substituent to enhance selectivity. These applications are supported by research published in the Journal of Medicinal Chemistry and Pest Management Science.
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