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2-bromo-4-chloro-1-(difluoromethyl)benzene
$450.00
CAS No.: 1261476-50-9
Catalog No.: 193899
Purity: 95%
MF: C7H4BrClF2
MW: 241.462
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC(=C1)Cl)C(F)F
Catalog No.: 193899
Purity: 95%
MF: C7H4BrClF2
MW: 241.462
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC(=C1)Cl)C(F)F
2-bromo-4-chloro-1-(difluoromethyl)benzene; CAS No.: 1261476-50-9;2-bromo-4-chloro-1-(difluoromethyl)benzene. PROPERTIES: 2-bromo-4-chloro-1-(difluoromethyl)benzene is a brominated, chlorinated, and fluorinated aromatic compound with molecular formula C8H6BrClF2. It typically exists as a colorless liquid with a boiling point around 130-135 C. The compound has limited water solubility but dissolves well in organic solvents like chloroform or diethyl ether. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic bromine and chlorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic systems. The bromo, chloro, and difluoromethyl substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions (The Journal of Organic Chemistry). In pharmaceutical development, 2-bromo-4-chloro-1-(difluoromethyl)benzene contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-withdrawing bromine, chlorine, and fluorine atoms modulate the electronic properties of derived materials (Advanced Materials).
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