2'-bromo-3'-chloroacetophenone
$300.00
CAS No.: 161957-60-4
Catalog No.: 193894
Purity: 95%
MF: C8H6BrClO
MW: 233.492
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC=C1Cl)C(C)=O
Catalog No.: 193894
Purity: 95%
MF: C8H6BrClO
MW: 233.492
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC=C1Cl)C(C)=O
2'-bromo-3'-chloroacetophenone; CAS No.: 161957-60-4;2'-bromo-3'-chloroacetophenone. PROPERTIES: 2'-bromo-3'-chloroacetophenone is a brominated and chlorinated aromatic ketone with molecular formula C9H7BrClO. It typically exists as a colorless to pale yellow liquid with a boiling point around 150-155 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or acetone. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic bromine and chlorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile building block for creating complex aromatic systems. The bromo and chloro substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions, while the ketone group enables condensation reactions to form Schiff bases or other imine derivatives (Tetrahedron Letters). In pharmaceutical development, 2'-bromo-3'-chloroacetophenone contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-withdrawing bromine and chlorine atoms modulate the electronic properties of derived materials (Journal of Materials Chemistry C).
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