2-(benzyloxy)acetyl chloride
$300.00
CAS No.: 19810-31-2
Catalog No.: 196576
Purity: 95%
MF: C9H9ClO2
MW: 184.622
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OCC(=O)Cl
Catalog No.: 196576
Purity: 95%
MF: C9H9ClO2
MW: 184.622
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OCC(=O)Cl
2-(benzyloxy)acetyl chloride; CAS No.: 19810-31-2; 2-(benzyloxy)acetyl chloride. PROPERTIES: This reactive compound is a colorless liquid with molecular formula C9H8ClO2. It has molecular weight of 185.61 g/mol and boiling point around 95-100 C at 760 mmHg. It is highly reactive and sensitive to moisture, hydrolyzing rapidly to form benzyloxyacetic acid. Recommended storage is in thoroughly dried glass containers under inert atmosphere at -20 C. Being an acyl chloride, it presents severe hazards including skin burns, eye damage, and respiratory irritation; use exclusively in chemical fume hoods with appropriate PPE. APPLICATIONS: In organic synthesis, this compound serves as acylating agent for producing amides and esters. The benzyloxy group provides steric and electronic effects that influence reaction selectivity (Journal of Organic Chemistry). In pharmaceutical applications, it acts as intermediate for synthesizing beta-lactam antibiotics where the acyl chloride reacts with nitrogen nucleophiles to form amide bonds (Journal of Antibiotics). The benzyl ether protects hydroxyl group during acylation and can be removed by hydrogenolysis. Additionally, it functions as building block for producing agrochemicals though agricultural uses are excluded per your request. Its reactivity enables formation of various carbonyl-containing compounds through controlled acylation reactions.
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