2-amino-4-hydroxypyrimidine-5-carboxylic acid
$200.00
CAS No.: 40769-70-8
Catalog No.: 192968
Purity: 95%
MF: C5H5N3O3
MW: 155.113
Storage: 2-8 degree Celsius
SMILES: NC1=NC=C(C(=N1)O)C(=O)O
Catalog No.: 192968
Purity: 95%
MF: C5H5N3O3
MW: 155.113
Storage: 2-8 degree Celsius
SMILES: NC1=NC=C(C(=N1)O)C(=O)O
2-amino-4-hydroxypyrimidine-5-carboxylic acid; CAS No.: 40769-70-8; 2-amino-4-hydroxypyrimidine-5-carboxylic acid. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C5H5N3O2 and a molecular weight of 147.11 g/mol. It demonstrates a melting point in the range of 220-224 C and shows good solubility in polar solvents such as water and methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 2-amino-4-hydroxypyrimidine-5-carboxylic acid may release irritating vapors upon heating. The amino and hydroxyl groups require careful handling in strongly acidic or basic environments. APPLICATIONS: In medicinal chemistry, 2-amino-4-hydroxypyrimidine-5-carboxylic acid serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its functional groups enable formation of bioactive esters and amides through esterification and amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrimidine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
Reviews
Write Your Own Review