2-amino-4-bromo-3-fluorobenzonitrile
$250.00
CAS No.: 1820620-31-2
Catalog No.: 193887
Purity: 95%
MF: C7H4BrFN2
MW: 215.025
Storage: 2-8 degree Celsius
SMILES: NC1=C(C#N)C=CC(=C1F)Br
Catalog No.: 193887
Purity: 95%
MF: C7H4BrFN2
MW: 215.025
Storage: 2-8 degree Celsius
SMILES: NC1=C(C#N)C=CC(=C1F)Br
2-amino-4-bromo-3-fluorobenzonitrile; CAS No.: 1820620-31-2;2-amino-4-bromo-3-fluorobenzonitrile. PROPERTIES: 2-amino-4-bromo-3-fluorobenzonitrile is a brominated and fluorinated aromatic amine nitrile with molecular formula C7H4BrFNN. It typically exists as a white to off-white crystalline powder with a melting point of approximately 125-130 C. The compound has limited water solubility but dissolves in basic aqueous solutions. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic nitrogen-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from moisture and heat. APPLICATIONS: In pharmaceutical research, this compound serves as a lead structure for developing antimicrobial and anticancer agents. The bromo and fluoro substitution provides electron-withdrawing effects that enhance binding to biological targets, while the amino and nitrile groups form the pharmacophore essential for activity (European Journal of Medicinal Chemistry). In materials science, 2-amino-4-bromo-3-fluorobenzonitrile contributes to the creation of functional organic materials with tailored electronic properties. Its fluorinated aromatic core and nitrile group influence the electronic characteristics of derived materials, useful in optoelectronic applications such as organic field-effect transistors (Journal of Materials Chemistry C). The amino group can be further functionalized through acylation or alkylation, expanding its utility in multistep syntheses (The Journal of Organic Chemistry).
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