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2-amino-3-fluorophenol; CAS No.: 53981-23-0; 2-amino-3-fluorophenol. PROPERTIES: This fluorinated phenolic amine features molecular formula C6H6FNO? with molecular weight 139.12 g/mol. It exists as a crystalline solid, exhibiting characteristic amine and phenol reactivity. Soluble in polar protic solvents like methanol and water, sparingly soluble in ethyl acetate. Melting point ranges 120-125 C. Shows IR absorption for hydroxyl and amine groups. Thermogravimetric analysis indicates decomposition above 200 C under nitrogen. Should be stored at 2-8 C in sealed containers, protected from moisture. May cause skin irritation and eye damage. APPLICATIONS: As a fluorinated amino phenol, 2-amino-3-fluorophenol serves as a building block in sulfa drug synthesis. It undergoes diazotization and coupling reactions to form bioactive azo derivatives in medicinal chemistry. Also used in preparing fluorescent probes for bioimaging, where its amine functionality enables conjugation via reductive amination. In materials science, it's a monomer for polyurethane foams, enhancing thermal stability through fluorine substituents.