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2,4-bis(trifluoromethyl)phenylboronic acid; CAS No.: 153254-09-2; 2,4-bis(trifluoromethyl)phenylboronic acid. PROPERTIES: This bis(trifluoromethyl)-substituted boronic acid features molecular formula C?H?F?O? with molecular weight 267.14 g/mol. Exists as a white powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 150-155 C. Exhibits IR absorption for boronic acid group. Thermogravimetric analysis indicates decomposition above 200 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a bis(trifluoromethyl)-substituted boronic acid, 2,4-bis(trifluoromethyl)phenylboronic acid is used in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate in constructing biaryl pharmaceuticals. Also used in materials science as monomer for preparing polyboronate hydrogels with tunable degradation rates.