2,2,2-trifluoro-1-(triphenylsilyl)ethanone
$450.00
CAS No.: 141334-25-0
Catalog No.: 193095
Purity: 95%
MF: C20H15F3OSi
MW: 356.419
Storage: 2-8 degree Celsius
SMILES: FC(C(=O)[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(F)F
Catalog No.: 193095
Purity: 95%
MF: C20H15F3OSi
MW: 356.419
Storage: 2-8 degree Celsius
SMILES: FC(C(=O)[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(F)F
2,2,2-trifluoro-1-(triphenylsilyl)ethanone; CAS No.: 141334-25-0; 2,2,2-trifluoro-1-(triphenylsilyl)ethanone. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C13H10F3OSi and a molecular weight of 279.28 g/mol. It exhibits a melting point in the range of 72-76 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 2,2,2-trifluoro-1-(triphenylsilyl)ethanone may cause skin irritation. The ketone group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 2,2,2-trifluoro-1-(triphenylsilyl)ethanone serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its trifluoro substituent enables improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The silyl-protected aldehyde group also facilitates controlled deprotection strategies in multi-step organic syntheses, as evidenced by methodological publications in synthetic chemistry.
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