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2,2,2-trifluoro-1-(2-fluorophenyl)ethanamine hydrochloride
$400.00
CAS No.: 2153472-91-2
Catalog No.: LT0005
Purity: 95%
MF: C8H8ClF4N
MW: 229.604
Storage: 2-8 degree Celsius
SMILES: Cl.FC(C(N)C1=C(C=CC=C1)F)(F)F
Catalog No.: LT0005
Purity: 95%
MF: C8H8ClF4N
MW: 229.604
Storage: 2-8 degree Celsius
SMILES: Cl.FC(C(N)C1=C(C=CC=C1)F)(F)F
For R&D use only. Not for human or animal use.
CAS NO.: 2153472-91-2;2,2,2-trifluoro-1-(2-fluorophenyl)ethanamine hydrochloride. PROPERTIES: This fluorinated amine salt appears as a white hygroscopic powder with a molecular weight of approximately 217.1 g/mol (free base). The 2,2,2-trifluoro-1-(2-fluorophenyl)ethanamine hydrochloride combines multiple fluorine substituents with an aromatic amine. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 2,2,2-trifluoro-1-(2-fluorophenyl)ethanamine hydrochloride serves as a key intermediate in the synthesis of various pharmaceuticals. Its fluorinated amine group provides opportunities for reductive amination and alkylation reactions. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The trifluoromethyl group enhances metabolic resistance in resulting drug candidates. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity.
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