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ethyl 2-(1-benzyl-3,3-difluoropiperidin-4-ylidene)acetate

ethyl 2-(1-benzyl-3,3-difluoropiperidin-4-ylidene)acetate

tert-butyl 4-((benzyloxycarbonylamino)methyl)-3,3-difluoropiperidine-1-carboxylate

tert-butyl 4-((benzyloxycarbonylamino)methyl)-3,3-difluoropiperidine-1-carboxylate

2-(1-(tert-butoxycarbonyl)-3,3-difluoropiperidin-4-yl)acetic acid

$450.00
CAS No.: 1373503-54-8
Catalog No.: 172036
Purity: 95%
MF: C12H19F2NO4
MW: 279.283
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CCC(CC(O)=O)C(F)(F)C1
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SKU
172036
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2-(1-(tert-butoxycarbonyl)-3,3-difluoropiperidin-4-yl)acetic acid; CAS No.: 1373503-54-8; ChemShuttle's expertise in Small molecules synthesis is demonstrated through 2-(1-(tert-butoxycarbonyl)-3,3-difluoropiperidin-4-yl)acetic acid. This fluorinated piperidine acetic acid serves as a key intermediate for renin inhibitor development. The acetic acid moiety mimics the transition state of angiotensinogen cleavage, while fluorine atoms enhance binding affinity. Applications include hypertension treatment research and cardiovascular drug discovery. The company provides IC50 data against human recombinant renin. Custom services include preparation of 18F-labeled versions for PET imaging of renin activity.

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