The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
1-tert-butyl 3-ethyl 5,5-difluoropiperidine-1,3-dicarboxylate; CAS No.: 1356339-26-8; ChemShuttle's role as a Leading Chemicals Distributor is highlighted by 1-tert-butyl 3-ethyl 5,5-difluoropiperidine-1,3-dicarboxylate. This difluorinated piperidine serves as a key intermediate for prodrug synthesis targeting esterase-mediated activation. The ethyl ester allows controlled hydrolysis to mono-acid intermediates, while the tert-butyl ester maintains protection during subsequent reactions. Applications include ACE inhibitor development and GABA analog prodrugs. The company provides comparative hydrolysis kinetic data across tissue esterases. Technical support includes optimization of formulation strategies for sustained release profiles.