1-(tert-butoxycarbonyl)-5,5-difluoropiperidine-2-carboxylic acid
$450.00
CAS No.: 1255663-95-6
Catalog No.: 171959
Purity: 95%
MF: C11H17F2NO4
MW: 265.256
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CC(F)(F)CCC1C(O)=O
Catalog No.: 171959
Purity: 95%
MF: C11H17F2NO4
MW: 265.256
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CC(F)(F)CCC1C(O)=O
1-(tert-butoxycarbonyl)-5,5-difluoropiperidine-2-carboxylic acid; CAS No.: 1255663-95-6; ChemShuttle's position as a custom synthesis companies member is evident in 1-(tert-butoxycarbonyl)-5,5-difluoropiperidine-2-carboxylic acid. This gem-difluorinated piperidine acid acts as a building block for fluorine-rich peptide analogs. The 5,5-difluoro substitution creates a gauche effect that preorganizes the ring conformation for optimal target binding. Applications include protease inhibitor development and fluorinated foldamer construction. The company offers custom synthesis of enantiomeric pairs to explore chirality-activity relationships. Technical data includes variable-temperature NMR studies confirming restricted ring puckering. Scale-up batches are accompanied by XRPD analysis to ensure consistent crystalline form for formulation development.
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