1-(difluoromethyl)-3-iodobenzene
$200.00
CAS No.: 1214372-71-0
Catalog No.: WLZ1566
Purity: 95%
MF: C7H5F2I
MW: 254.017
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC(=CC=C1)I)F
Catalog No.: WLZ1566
Purity: 95%
MF: C7H5F2I
MW: 254.017
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC(=CC=C1)I)F
CAS NO.: 1214372-71-0; 1-(difluoromethyl)-3-iodobenzene. PROPERTIES: This halogenated aromatic compound features a difluoromethyl group and an iodine substituent on a benzene ring, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The 1-(difluoromethyl)-3-iodobenzene typically appears as a colorless to pale yellow liquid with moderate solubility in common organic solvents. Its molecular structure includes an electrophilic iodine atom that renders the molecule reactive toward nucleophilic substitution reactions. For optimal stability and to prevent premature reactions, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves and safety goggles are recommended. This compound is sensitive to light and moisture, requiring careful environmental control during storage and use. In case of skin contact, wash thoroughly with soap and water; if eye contact occurs, rinse immediately and seek medical evaluation. APPLICATIONS: The 1-(difluoromethyl)-3-iodobenzene serves as a versatile building block in organic synthesis, particularly for creating iodinated bioactive molecules. The iodine substituent provides a handle for cross-coupling reactions, enabling the creation of substituted benzene derivatives with diverse biological activities. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The difluoromethyl group contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound can benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.
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