1-bromo-2-chloro-4-fluoro-5-methoxybenzene
$300.00
CAS No.: 1823372-35-5
Catalog No.: 193836
Purity: 95%
MF: C7H5BrClFO
MW: 239.471
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C(=C1)OC)F)Cl
Catalog No.: 193836
Purity: 95%
MF: C7H5BrClFO
MW: 239.471
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C(=C1)OC)F)Cl
1-bromo-2-chloro-4-fluoro-5-methoxybenzene; CAS No.: 1823372-35-5;1-bromo-2-chloro-4-fluoro-5-methoxybenzene. PROPERTIES: 1-bromo-2-chloro-4-fluoro-5-methoxybenzene is a multiply halogenated aromatic compound with molecular formula C6H4BrClFO. It typically exists as a colorless liquid with a mild aromatic odor, having a boiling point around 135-140 C. The compound has limited water solubility but dissolves well in organic solvents like chloroform or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic halogen-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a building block for creating functionalized aromatic systems. The bromo, chloro, and fluoro substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions, while the methoxy group offers electron-donating effects that influence reactivity (Synthesis). In pharmaceutical research, 1-bromo-2-chloro-4-fluoro-5-methoxybenzene contributes to the development of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a precursor for creating organic semiconductors with tailored electronic properties, where the electron-withdrawing halogens modulate charge transport characteristics (Journal of Materials Chemistry C).
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