1,7-naphthyridin-3-amine
$400.00
CAS No.: 58680-42-5
Catalog No.: 192760
Purity: 95%
MF: C8H7N3
MW: 145.165
Storage: 2-8 degree Celsius
SMILES: N1=CC(=CC2=CC=NC=C12)N
Catalog No.: 192760
Purity: 95%
MF: C8H7N3
MW: 145.165
Storage: 2-8 degree Celsius
SMILES: N1=CC(=CC2=CC=NC=C12)N
1,7-naphthyridin-3-amine; CAS No.: 58680-42-5; 1,7-naphthyridin-3-amine. PROPERTIES: This naphthyridine amine has molecular formula C6H6N3. It generally appears as a pale yellow crystalline powder. The 1,7-naphthyridin-3-amine demonstrates limited water solubility but good solubility in polar aprotic solvents like DMSO and DMF. Its melting point ranges between 190-195 C, and it has a molecular weight of approximately 132.13 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive products upon exposure to heat or shock. In case of spillage, neutralization with a mild acid followed by disposal as hazardous waste is recommended. APPLICATIONS: The 1,7-naphthyridin-3-amine serves as a valuable intermediate in the synthesis of muscarinic receptor antagonists for respiratory disorders where the naphthyridine ring provides essential hydrogen bonding interactions with receptor residues (as detailed in medicinal chemistry literature). The amine group forms additional hydrogen bonds with receptor subtypes. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The amine group can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
Reviews
Write Your Own Review