1,3-diphenyl-1H-pyrazole-5-carboxylic acid
$300.00
CAS No.: 964-42-1
Catalog No.: 192885
Purity: 95%
MF: C16H12N2O2
MW: 264.284
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)N1N=C(C=C1C(=O)O)C1=CC=CC=C1
Catalog No.: 192885
Purity: 95%
MF: C16H12N2O2
MW: 264.284
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)N1N=C(C=C1C(=O)O)C1=CC=CC=C1
1,3-diphenyl-1H-pyrazole-5-carboxylic acid; CAS No.: 964-42-1; 1,3-diphenyl-1H-pyrazole-5-carboxylic acid. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C15H12N2O2 and a molecular weight of 252.27 g/mol. It demonstrates a melting point in the range of 178-182 C and shows moderate solubility in common organic solvents like methanol and dichloromethane. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 1,3-diphenyl-1H-pyrazole-5-carboxylic acid may cause skin irritation. The carboxylic acid group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, 1,3-diphenyl-1H-pyrazole-5-carboxylic acid serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrazole derivatives. Its phenyl substituents enable improved lipophilicity for enhanced membrane permeability. Additionally, this compound functions as a building block for preparing liquid crystalline materials through formation of mesogenic units. Academic research has explored its utility in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrazole ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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