1-(2-aminophenyl)ethanone
$250.00
CAS No.: 551-93-9
Catalog No.: LT0262
Purity: 95%
MF: C8H9NO
MW: 135.166
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=CC=C1)C(C)=O
Catalog No.: LT0262
Purity: 95%
MF: C8H9NO
MW: 135.166
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=CC=C1)C(C)=O
CAS NO.: 551-93-9;1-(2-aminophenyl)ethanone. PROPERTIES: This aminophenyl ketone presents as a white crystalline solid with a molecular weight of approximately 149.2 g/mol. The 1-(2-aminophenyl)ethanone combines an acetophenone framework with an amino group. It exhibits limited aqueous solubility but good dissolution in ethyl acetate and methanol. Stability characterization reveals sensitivity to oxidation and acid-catalyzed amine protonation, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 1-(2-aminophenyl)ethanone serves as a key intermediate in the synthesis of various pharmaceuticals. Its aminophenyl ketone framework provides opportunities for constructing beta-blockers and nonsteroidal anti-inflammatory agents. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The amino group undergoes acylation or sulfonation for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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