ULM-1(MDK7526; (S,R,S)-AHPC; Protein degrader 1)
$200.00
CAS No.: 1448297-52-6
Catalog No.: 133776
Purity: 95%
MF: C22H30N4O3S
MW: 430.574
Storage: 2-8 degree Celsius
SMILES: CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)C=C1
Catalog No.: 133776
Purity: 95%
MF: C22H30N4O3S
MW: 430.574
Storage: 2-8 degree Celsius
SMILES: CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)C=C1
CAS NO.: 1448297-52-6; (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ULM-1(MDK7526; (S,R,S)-AHPC; Protein degrader 1)). PROPERTIES: (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is a chiral compound with specific stereochemistry. It has a molecular formula that reflects its complex structure. It is likely to be a solid at room temperature. Storage should be under controlled conditions, preferably in a refrigerator to maintain its stability. In terms of safety, as with many bioactive compounds, it should be handled with care to avoid ingestion and contact with the body. APPLICATIONS: It is prominently used in the field of protein degradation research. As a protein degrader, it can be designed to target specific proteins for degradation. This is achieved through its interaction with E3 ubiquitin ligases and the target protein, leading to the ubiquitination and subsequent degradation of the target protein by the proteasome. Such applications are valuable in studying the function of proteins by selectively removing them from the cell. The use of this compound in protein degradation research is supported by numerous scientific studies in the area of chemical biology and proteomics.
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